Expression and Purification of HCV Core and Core-E1E2 Proteins in Different Bacterial Strains
نویسندگان
چکیده
منابع مشابه
expression and purification of hcv core and core-e1e2 proteins in different bacterial strains
background: hepatitis c virus (hcv) is a main public health problem causing chronic liver infection and subsequently liver cirrhosis and lethal hepatocellular carcinoma (hcc). vaccination based on hcv capsid proteins has attracted a special interest for prevention of viral infections. the core protein is a basic and evolutionary most conserved protein, which regulates the cellular processes rel...
متن کاملExpression and Purification of HCV Core and Core-E1E2 Proteins in Different Bacterial Strains.
BACKGROUND Hepatitis C virus (HCV) is a main public health problem causing chronic liver infection and subsequently liver cirrhosis and lethal hepatocellular carcinoma (HCC). Vaccination based on HCV capsid proteins has attracted a special interest for prevention of viral infections. The core protein is a basic and evolutionary most conserved protein, which regulates the cellular processes rela...
متن کاملDifferent protein expression systems can influence the direction of the immune responses against HCV core protein in animal model
Introduction: Hepatitis C virus (HCV) infection is a major public health problem which influences about 170 million people worldwide. Different types of vaccines have been designed using HCV structural proteins to control the viral infection. The core nucleocapsid protein is one of the most conserved proteins and a desirable target for HCV vaccines, especially the protein-based vaccines. In cur...
متن کاملHCV core antigen and HCV-RNA in HIV/HCV co-infected patients with different HCV genotypes
BACKGROUND A good correlation between HCV core antigen (HCVAg) and different HCV-RNA assays has been described, but little data are available in HCV/HIV co-infection. We aimed to evaluate HCVAg in comparison with HCV-RNA and to determine their kinetics during antiviral treatment in selected HCV/HIV co-infected patients. METHODS 355 samples from 286 HCV/HIV co-infected subjects for whom HCV-RN...
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ژورنال
عنوان ژورنال: Iranian Journal of Biotechnology
سال: 2015
ISSN: 1728-3043,2322-2921
DOI: 10.15171/ijb.1249